We have been waiting for Brady's ataxia to improve, but unfortunately, we haven't seen much of a change in his balance or coordination. I spoke with Dr. Katherman today concerning Brady's continued wobbliness and unsteadiness on his feet. The weakness appears to be in all four legs. Yesterday morning he fell down the last three steps going downstairs and that really prompted me to call her. Also he now has to wear booties on his front paws during our morning walks due to his toenails dragging on the pavement and wearing down to the point of where they bleed. :(
Her recommendation is to decrease his phenobarbital from 97.2mg twice a day to 64.8mg twice a day. We want to gain significant seizure control, but we also want him to be able to walk and function properly without the fear of him falling down and injuring himself.
Brady is scheduled to see Dr. Katherman on Thursday, February 25th to check the trough level of Zonisamide and to check a Potassium Bromide level. Those results will tell us if the Zonisamide was increased too much on January 26. The Potassium Bromide will be at a steady state by then since he has been on the increased dose of that medicine for 4 months. Remember everytime you increase Potassium Bromide it will take 4 months for it to reach a steady state. KBr was increased to 600mg at the end of October. (2ml three times a day)
Those blood draws will give us insight on where the levels are with those two drugs. As of today Brady has been 3 weeks seizure free and we continue to pray that it will remain that way.
Tuesday, February 16, 2010
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